Figure 2.

CD4, CD8A and FOXP3 mRNA expression in breast cancer. TPM of (A) CD4, (B) CD8A and (C) FOXP3 obtained from The Cancer Genome Atlas database were compared between BC and healthy breast tissue samples. TPM of (D) CD4, (E) CD8A and (F) FOXP3 were compared among BC patients at different clinical stages. *P<0.01. All experiments were repeated three times. CD, cluster of differentiation; BRCA, Breast invasive carcinoma; BC, breast cancer; FOXP3, forkhead box protein P3; TPM, transcripts per million; num(T), number of tumor samples; num(N), number of normal tissue samples.