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. 2018 Sep 5;18(5):4247–4258. doi: 10.3892/mmr.2018.9460

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Copyright: © Meng et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 5. — Influence of Tregs on the cytokine secretion of T cells. (A) Representative flow cytometry demonstrating the association between Treg quantity and cytokine secretion of T cells in tumors. Comparison of CD4⁺T cell secretion of (B) IFN-γ, (C) IL-4 and (D) IL-17 and (E) CD8⁺T cell cytokine secretion between Treg low and Treg high BC patients. All experiments were repeated three times. Treg, regulatory T cell; BC, breast cancer; CD, cluster of differentiation; IFN, interferon; IL, interleukin.