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. 2018 Sep 5;18(5):4247–4258. doi: 10.3892/mmr.2018.9460

Table I.

Association of tumor infiltrating lymphocytes with clinicopathological characteristics of breast cancer patients.

Characteristics Total N TILs low N (%) TILs high N (%) P-value
Age 0.976
  <50 years 26 18 (69.2)   8 (30.8)
  ≥50 years 46 32 (69.6) 14 (30.4)
Tumor size 0.100
  <2 cm 30 24 (80.0)   6 (20.0)
  ≥2 cm 42 26 (61.9) 16 (38.1)
Lymph node 0.409
  Negative 38 28 (73.7) 10 (26.3)
  Positive 34 22 (64.7) 12 (35.3)
Histological grade 0.030
  Low (I and II) 40 32 (80.0)   8 (20.0)
  High (III) 32 18 (56.3) 14 (43.8)
ER 0.006
  Negative 23 11 (47.8) 12 (52.2)
  Positive 49 39 (79.6) 10 (20.4)
HER2 status 0.047
  Negative 48 37 (77.1) 11 (22.9)
  Positive 24 13 (54.2) 11 (45.8)
Ki-67 0.113
  <20% 33 26 (78.8)   7 (21.2)
  ≥20% 39 24 (61.5) 15 (38.5)
Molecular subtype 0.012
  Luminal 37 31 (83.8)   6 (16.2)
  Her2+ 24 13 (54.2) 11 (45.8)
  Triple-negative 11   5 (45.5)   6 (54.5)

TILs, tumor infiltrating lymphocytes; ER, estrogen receptor; HER2, human epidermal growth factor receptor 2.