Table III.
Epidermal growth factor receptor-tyrosine kinase inhibitory activity of target molecules.
| Compound | IC50 (in µM) |
|---|---|
| 1a | 112.45±21.52 |
| 1b | 34.05±4.11 |
| 1c | 8.45±0.65 |
| 1d | 2.54±0.22 |
| Dacomitinib | 0.06±0.01 |
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