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. 2018 Sep 4;18(5):4417–4427. doi: 10.3892/mmr.2018.9450

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Copyright: © Yu et al.

This is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.

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Figure 7. — Effect of GB and GK on neurotrophic factors BDNF and GDNF in OGD astrocytes. Primary astrocytes were exposed to OGD for 3 h. At the beginning of re-oxygenation, GB and GK (30 µg/ml, dissolved in DMSO) were added. The same volume of DMSO was added as a control. Following 24 h, the cells were collected to measure the expression of BDNF and GDNF by western blotting. Semi-quantitative results are presented as the mean ± standard error of the mean, and analyzed from three independent experiments with similar results. *P<0.05, as indicated. GB, ginkgolide B; GK, ginkgolide K; OGD, oxygen-glucose deprivation; BDNF, brain derived neurotrophic factor; GDNF, glial cell derived neurotrophic factor; DMSO, dimethyl sulfoxide.