Table 1. Disease-modifying drugs available in argentina during the two analyzed time periods.
| Period | Drug | Administration method | Frequency of use |
|---|---|---|---|
| Before 2010 | IFNβ-1b | SC | Day by half |
| IFNβ-1a-IM | IM | Once per week | |
| IFNβ-1a-SC | SC | Three times per week | |
| GA | SC | Daily | |
| Cyclophosphamide | Intravenous | From monthly to six monthly | |
| Mitoxantrone | Intravenous | Every three months | |
| After 2010 | Fingolimod | Oral | Daily |
| Natalizumab | Intravenous | Monthly | |
| Alemtuzumab | Intravenous | Annual | |
| Teriflunomide | Oral | Daily | |
| Dimethyl fumarate | Oral | Twice daily |
GA: glatiramer acetate, IFN: interferon, IM: intramuscular, SC: subcutaneous.