Table 2.
Self-reported Relief of Gastroesophageal Reflux Symptoms after Switching from a PPI to Vonoprazan.
| Outcome | Number of patients (%) | Odds ratio (95% CI) | p value | |||
|---|---|---|---|---|---|---|
| NERD (n=26) | ||||||
| Self-reported relief of symptoms | ||||||
| Improvement | 18 (69.2) | 9.0 (2.2-80.3) | <0.001 | |||
| No change | 6 (23.1) | |||||
| Exacerbation | 2 (7.7) | |||||
| PPI-resistant NERD (n=19) | ||||||
| Self-reported relief of symptoms | ||||||
| Improvement | 12 (63.2) | 6.0 (1.3-55.2) | 0.013 | |||
| No change | 5 (26.3) | |||||
| Exacerbation | 2 (10.5) |
NERD: reflux esophagitis and non-erosive reflux disease, CI: confidence interval, PPI: proton pump inhibitor
Bolding indicates statistical significance (p<0.05).