Table 3.
Comparison of Patients Diagnosed by Updated Criteria for Sub-clinical Cushing’s Syndrome and Those Diagnosed by Criteria Widely Used in Japan.
| Patients diagnosed as sub-clinical Cushing’s syndrome by the criteria of widely used in Japan. | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Sex | Age (years) |
Tumor laterality |
Tumor size (mm) |
Morning serum cortisol (µg/dL) |
Serum cortisol after 1mg DST (µg/dL) |
Complications | ||||||
| F | 76 | right | 8 | 11.3 | 8.3 | hypokalemia | ||||||
| F | 53 | left | 26 | 10.9 | 6.2 | hypertension | ||||||
| F | 61 | right | 17 | 14.2 | 6.1 | diabetes mellitus, dyslipidemia, hypokalemia | ||||||
| F | 44 | right | 16 | 11.1 | 3.2 | hypertension, hypokalemia | ||||||
| M | 60 | left | 23 | 10.6 | 5.5 | hypertension, diabetes mellitus, hypokalemia | ||||||
| Patients diagnosed as sub-clinical Cushing’s syndrome only by updated criteria | ||||||||||||
| Sex |
Age
(years) |
Tumor
laterality |
Tumor
size (mm) |
Morning
serum cortisol (µg/dL) |
Serum cortisol
after 1mg DST (µg/dL) |
Complications | ||||||
| F | 55 | left | 16 | 12.2 | 1.9 | hypokalemia | ||||||
| F | 69 | right | 20 | 12.1 | 1.8 | hypertension | ||||||
| F | 59 | right | 14 | 14.7 | 2.3 | hypertension, diabetes mellitus, dyslipidemia | ||||||
| M | 45 | left | 18 | 16.1 | 1.9 | hypertension, diabetes mellitus, hypokalemia | ||||||
| F | 66 | left | 21 | 12.8 | 1.9 | hypertension, diabetes mellitus, hypokalemia | ||||||
There was not significant difference between patients diagnosed only by updated criteria for SCS and those diagnosed by criteria commonly used in Japan at the point of sex, age, tumor laterality, tumor size, value of morning serum cortisol, and complications (each p>0.05). The significance of differences between means was estimated by the Student’st-test. p<0.05 was considered significant.