Hypertensive disorders of pregnancy are associated with immune, vascular, and hormonal factors that can cause detrimental long-lasting effects in both mother and baby. AT1-AA, ANG II type 1 receptor agonistic autoantibodies; NK, natural killer; RAAS, renin-angiotensin-aldosterone system; sFlt-1, soluble fms-like tyrosine kinase-1; SNS, sympathetic nervous system; Th1, T helper 1; Th17, T helper 17.