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. 2018 Apr 18;315(3):R434–R441. doi: 10.1152/ajpregu.00014.2018

Fig. 1.

Fig. 1.

Experiment 1. Licks (means ± SE) for conditioned stimulus (CS− and CS+) flavored solutions paired with intragastric (IG) infusions of water and 5% soybean oil, respectively, during 1-bottle tests and without IG infusions during 2-bottle tests. Left: the mice drank (1 h/day) a CS− flavored solution paired with IG water infusions in test 0 (mean of the last 2 CS- sessions) and a CS+ flavored solution paired with IG 5% soybean oil infusions in tests 1–3. The orlistat (ORL) group (n = 10) was infused with oil + orlistat and the control (CON) group (n = 10) was infused with oil without orlistat. Right: 1-h licks (means +SE) of CS− and CS+ during the 2-day 2-bottle tests 1 (ORL1, CON 1) and 2 (ORL 2, CON 2). Number above bar represents mean percent preference for the CS+ solution. #Significant differences (P < 0.05) between 1-bottle tests 0 and tests 1–3 licks and between 2-bottle CS+ vs. CS− licks. *Significant difference (P < 0.05) between orlistat and control group CS+ licks.