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NM922 attenuates left ventricular (LV) dilation and dysfunction after transverse aortic constriction (TAC). Echocardiography was performed at baseline and every 2 wk after TAC to assess LV end-systolic diameter (LVESD; A), LV end-diastolic diameter (LVEDD; B), LV posterior wall thickness at diastole (LVPWd; C), and LV ejection fraction (LVEF; D). n = 15 mice/study group. *P < 0.05 and **P < 0.01 vs. vehicle.
