Table 1.

Steady-state parameters of cardiac function as assessed by cardiac pressure-volume catheterization

	Sham Group	Sham + B Group	VO Group	VO + B Group
Heart rate, beats/min	327 ± 25	298 ± 32	304 ± 33	327 ± 30
Cardiac output, ml/min	59 ± 6	60 ± 6	134 ± 25*	98 ± 18*†
End-diastolic volume, µl	305 ± 14	330 ± 47	802 ± 115*	504 ± 101*†
End-systolic volume, µl	141 ± 19	128 ± 18	411 ± 46*	263 ± 57*†
End-diastolic pressure, mmHg	6 ± 1	17 ± 2	11 ± 3*	9 ± 2*
End-systolic pressure, mmHg	102 ± 13	101 ± 10	91 ± 10	91 ± 14
Stroke volume, µl	180 ± 15	211 ± 32	417 ± 58*	297 ± 49*†
Arterial elastance, mmHg/µl	0.57 ± 0.08	0.51 ± 0.07	0.17 ± 0.07*	0.35 ± 0.11*†

Values are means ± SE; n = 4–8 animals/group. Animals were divided into the following four groups: sham surgery (sham group), sham + LOX inhibitor (β-aminopropionitrile; sham + B group), VO surgery (VO) group, and VO + LOX inhibitor (VO + B group).

^*P < 0.05 vs. the sham group.

^†P < 0.05 vs. the VO group.