Table 2.

Associations between clinicopathologic variables and SII

Characteristics	Mean	s.e.m.	Median	P-value
Age (years)
< 65	857.17	50.70	637.76	0.36
≥ 65	866.76	81.21	697.67
Gender
Male	898.28	56.40	650.76	0.35
Female	786.47	63.49	637.76
Histologic grade
Mod/well differentiated	862.53	49.40	699.31	0.27
Poorly differentiated	818.38	87.84	585.0
Primary site
Colon	884.17	47.35	697.67	0.07
Rectum	737.66	99.95	595.71
T-stage
T1–3	897.49	60.33	675.11	0.55
T4	784.97	58.11	613.79
LN status
pN0	933.26	94.50	694.81	0.28
pN+	827.44	48.37	637.94
MMR status
dMMR	897.14	195.05	747.13	0.71
pMMR	857.63	44.17	648.99
Metastatic sites
Liver	877.09	53.67	668.48	0.43
Extrahepatic disease	831.49	71.88	639.15
No. of metastatic organs
Single	797.31	51.82	607.71	0.02
Multiple	969.17	74.88	775.77

SII systemic immune-inflammation index, LN lymph node