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The GBB consists of a mucus layer, a monolayer of epithelial cells, and a monolayer of endothelial cells that line blood vessels. This barrier protects the host by preventing passage of harmful compounds or pathogens from the gut lumen to the bloodstream. Transcellular and paracellular transport and junctional complexes and desmosomes are indicated. Figure created in biorender (http://biorender.io).
