Figure 7.

Phagocytosis and killing of bacteria by airway neutrophils significantly improves after antibiotic therapy in bronchiectasis. (A and B) n = 8 in stable state and n = 6 at the start and end of exacerbation. Airway neutrophils were isolated and phagocytosis and killing of green fluorescent protein PAO1 assessed as previously described. Unpaired Student’s t tests were used for comparison of stable state with start and end of exacerbation, and paired Student’s t tests were used for comparison of start with end of exacerbation. Pooled data are presented as mean ± SEM for phagocytosis data and median (interquartile range) for bacterial killing data. Bx = bronchiectasis; exac = exacerbation.