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mPG-1 induced changes in gene expression are inhibited by picropodophyllin (PPP: an IGF1R inhibitor) (A) IPEC-J2 cells were treated with PPP (10 μM) prior to the mPG-1 (9 μM) for 3 h, RNA was isolated, and expression of pro-inflammatory cytokines and cell migration markers (B) was assessed using qRT-PCR. Bars represent the mean ± SEM of three experiments; ns, Not Significant, *p < 0.05, **p < 0.01 and ***p < 0.001 as calculated by a one-way ANOVA post hoc Tukey test.
