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. 2018 Sep 25;7:F1000 Faculty Rev-1544. [Version 1] doi: 10.12688/f1000research.15860.1

Figure 3. Pushing and pulling to drive kinetic processes.

Figure 3.

( A) Pulling on adhesions and membrane can break intra-molecular and inter-molecular bonds, cause movement of adhesions on the membrane, and create undulations on the cell–cell adhesion interface. ( B) Pushing parallel to the lateral membrane can disengage and disperse adhesions, resulting in mixing of the membrane components. Pushing orthogonal to the lateral membrane can increase cell–cell contact area and time to enhance adhesion engagement.