Table 3.

Clinical data of affected individuals^*

Case	Age (y)	Sex	PDB	LGMD	AgeDx PDB(y)	AgeDx LGMD (y)	Treatment	Activity Level
1	48	F	+	+	34	44	None	Difficulty going up stairs and raising arms, back/leg pain, lumbar lordosis, wide based gait
2	47	M	−	+	−	45	None	Weakness in proximal arm and leg muscles
3	49	F	+	+	44	48	Previous bisphosphonates	Difficulty climbing stairs, lifting arms, extremity atrophy of extremities, lordotic posture, waddling gait
4	57	M	+	+	42	54	Calcitonin and bisphosphonates	Walks slowly with cane, severe pain and tenderness in spine and hip
5	33	M	+	-	31	-	Analgesics and calcitonin	Walks slowly with a limp, tenderness in back, pain in hip
6	50	M	+	+	38	38	None	Bedridden for several months, left side hemiparesis from stroke
7	47	F	+	+	45	45	Alendronate, cyclobenzaprine	Difficulty sitting, getting up from chair, back pain and weakness of the arms and hips
8	46	M	−	+	-	40	None	Unable to run, difficulty with stairs
9	64	M	+	+	37	40	None	Wheelchair bound, loss of sensation in extremities
10	59	M	+	+	UK	51	None	Bedridden 3 y prior to death, winging of the scapulae, weakness of trunk & lower extremities
11	61	M	+	+	61	UK	None	Difficulty walking, pain in spine and pelvis and femur
MEAN	50.9	3F/8M	9	10	41.5	45.6

^*+ = present; − = absent; UK = unknown