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. Author manuscript; available in PMC: 2018 Oct 5.
Published in final edited form as: Scifed J Cardiol. 2017 Jul 22;1(1):1000004.

Figure 1.

Figure 1

Effect of tetrahydrocannbinoid (THC) from marijuana use and its downstream activation of arachidonyl-ethanolamide (AEA) and 2-Arachidonoylglycerol (2AG) on inflammation and platelet activation at the tissue level. Therapeutic strategies involving aspirin and P2Y12 inhibitor, such as clopidogrel have shown retardation of platelet aggregation in target subjects

Abbreviations: GP – Glycoprotein, PI 3 kinase – Phosphoinositol-3-kinase, AKT – protein kinase B, MLC – Myosin Light Chain, ATP – Adenosine triphosphate, CXCL –CXC motif chemokine (aka stromal cell-derived factor)”