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. 2018 Sep 11;9(71):33601–33620. doi: 10.18632/oncotarget.26035

Figure 4. Probable activities of compound K against cognitive impairment.

Figure 4

(A) Compound K inhibits mTOR pathway in astrocyte, leading to autophagy-dependent Aβ clearance. (B) Compound K produces anti-inflammatory activity in microglia by inhibiting ROS generation and MAPK pathway. (C) Compound K prevents mitochondrial dysfunction and activates antioxidant signal in neurons, possibly leading to protective activity against cell death.