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. 2018 Oct 5;13(10):e0198231. doi: 10.1371/journal.pone.0198231

Table 4. Univariate analysis for association between gene profile and clinico-pathological features in the study cohorts.

(a) RCC
GAS5 miR-34a
p ass r (p corr) p ass r (p corr)
Age 0.239 -0.069 (0.598) 0.352 -0.066 (0.619)
Sex 0.631 0.063 (0.635) 0.798 -0.033(0.801)
Location 0.908 -0.015 (0.910) 0.884 0.019 (0.886)
HPD 0.257 0.191 (0.143) 0.504 -0.130(0.321)
Grade 0.402 0.171 (0.192) 0.378 -0.167 (0.204)
Tumor size 0.199 0.157 (0.230) 0.361 -0.152 (0.246)
LN 0.193 0.169 (0.195) 0.258 -0.147(0.261)
Recurrence 0.192 0.170 (0.195) 0.371 -0.116 (0.376)
DFS 0.120 0.305 (0.018) 0.363 0.215 (0.099)
OS 0.266 0.283 (0.029) 0.441 0.191 (0.144)
(b) GB
Age 0.883 0.063 (0.663) 0.930 -0.013 (0.931)
Sex 0.921 -0.014 (0.922) 0.514 -0.093 (0.520)
Location 0.530 -0.150 (0.300) 0.711 0.091 (0.531)
Recurrence 0.258 0.166 (0.248) 0.070 -0.260 (0.068)
DFS 0.869 0.012 (0.936) 0.677 0.074 (0.609)
OS 0.451 0.48 (0.743) 0.356 0.013 (0.927)
(c) HCC
Age 0.869 -0.037 (0.848) 0.059 -0.289 (0.121)
Sex 0.553 0.112 (0.556) 0.420 0.156 (0.411)
Hepatomegaly 0.692 -0.079 (0.680) 0.851 0.039 (0.837)
Tumor size 0.226 0.278 (0.137) 0.209 -0.315 (0.090)
Number of lesions 0.193 -0.352 (0.056) 0.916 0.112 (0.225)
CTP class 0.283 -0.206 (0.275) 0.533 0.122 (0.521)
Treatment 0.715 0.144 (0.447) 0.598 0.006 (0.973)

p ass p values for association, r (p corr) correlation spearman's coefficient and p value of correlation, HPD histopathological diagnosis, T tumor size, LN lymph node, DFS disease-free survival, OS overall survival, CTP Child-Turcotte-Pugh classification for liver cell failure. Spearman's rank, Mann-Whitney U and Kruskal-Wallis tests were used. Statistically significant values (p < 0.05) are shown in bold.