Table 4. Univariate analysis for association between gene profile and clinico-pathological features in the study cohorts.
(a) RCC | |||||
GAS5 | miR-34a | ||||
p ass | r (p corr) | p ass | r (p corr) | ||
Age | 0.239 | -0.069 (0.598) | 0.352 | -0.066 (0.619) | |
Sex | 0.631 | 0.063 (0.635) | 0.798 | -0.033(0.801) | |
Location | 0.908 | -0.015 (0.910) | 0.884 | 0.019 (0.886) | |
HPD | 0.257 | 0.191 (0.143) | 0.504 | -0.130(0.321) | |
Grade | 0.402 | 0.171 (0.192) | 0.378 | -0.167 (0.204) | |
Tumor size | 0.199 | 0.157 (0.230) | 0.361 | -0.152 (0.246) | |
LN | 0.193 | 0.169 (0.195) | 0.258 | -0.147(0.261) | |
Recurrence | 0.192 | 0.170 (0.195) | 0.371 | -0.116 (0.376) | |
DFS | 0.120 | 0.305 (0.018) | 0.363 | 0.215 (0.099) | |
OS | 0.266 | 0.283 (0.029) | 0.441 | 0.191 (0.144) | |
(b) GB | |||||
Age | 0.883 | 0.063 (0.663) | 0.930 | -0.013 (0.931) | |
Sex | 0.921 | -0.014 (0.922) | 0.514 | -0.093 (0.520) | |
Location | 0.530 | -0.150 (0.300) | 0.711 | 0.091 (0.531) | |
Recurrence | 0.258 | 0.166 (0.248) | 0.070 | -0.260 (0.068) | |
DFS | 0.869 | 0.012 (0.936) | 0.677 | 0.074 (0.609) | |
OS | 0.451 | 0.48 (0.743) | 0.356 | 0.013 (0.927) | |
(c) HCC | |||||
Age | 0.869 | -0.037 (0.848) | 0.059 | -0.289 (0.121) | |
Sex | 0.553 | 0.112 (0.556) | 0.420 | 0.156 (0.411) | |
Hepatomegaly | 0.692 | -0.079 (0.680) | 0.851 | 0.039 (0.837) | |
Tumor size | 0.226 | 0.278 (0.137) | 0.209 | -0.315 (0.090) | |
Number of lesions | 0.193 | -0.352 (0.056) | 0.916 | 0.112 (0.225) | |
CTP class | 0.283 | -0.206 (0.275) | 0.533 | 0.122 (0.521) | |
Treatment | 0.715 | 0.144 (0.447) | 0.598 | 0.006 (0.973) |
p ass p values for association, r (p corr) correlation spearman's coefficient and p value of correlation, HPD histopathological diagnosis, T tumor size, LN lymph node, DFS disease-free survival, OS overall survival, CTP Child-Turcotte-Pugh classification for liver cell failure. Spearman's rank, Mann-Whitney U and Kruskal-Wallis tests were used. Statistically significant values (p < 0.05) are shown in bold.