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. 2018 Oct 5;13(10):e0205067. doi: 10.1371/journal.pone.0205067

Fig 7. Pharmacologic interventions do not prevent the VSMC phenotype switch.

Fig 7

(A) mRNA expression of right carotid arteries subjected to 20min transient ligation and 72h reperfusion. Mice were either treated with TNF scavenging antibody/sham antibody, N-Acetylcysteine/Saline or Cytosporone B/sham gel. Statistical evaluation was performed by using a one-way ANOVA with Tukey’s multiple comparison post hoc test. n≥9. (B) mRNA expression of right carotid arteries subjected to 20min transient ligation followed by reperfusion periods as indicated. Arteries were either exposed to 1μM Sorafenib or sham (DMSO) treatment. Statistical evaluation was performed by using a two way ANOVA with Bonferroni’s post hoc test. n≥6.