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. 2018 Oct 5;13(10):e0205036. doi: 10.1371/journal.pone.0205036

Fig 1. PAR induction of PA3720-armR and mexAB-oprM expression.

Fig 1

Expression of PA3720, armR and mexA was assessed in log-phase WT P. aeruginosa strain K767 following a 30-minute exposure to the MIC of the AG, paromomycin (PAR; 256 μg/ml) using qRT-PCR. mexA expression was also assessed in a ΔarmR derivative of K767, K3415, following exposure (30 min) to the MIC of PAR (256 μg/ml) using qRT-PCR. In all cases, expression was normalized to rpoD and is reported relative to the untreated WT P. aeruginosa strain K767 (fold-change). Values shown are means ± standard errors of the means (SEMs) from at least three independent determinations, each performed in triplicate. t-test: *, P < 0.05; ***, P < 0.001.