Table 3. Impact of amgS gain-of-function mutations on antibiotic susceptibility.

Strain	AmgSa	MIC (μg/ml) for:b
		CAR	CAM	NAL	NOV
K767	WT	64	64	128	1024
K3260	V121G	64	32	128	2048
K3249	R182C	64	64	128	1024

^aThe amino acid change in AmgS in the indicated mutants is highlighted. WT, wild type.

^bCAR, carbenicillin; CAM, chloramphenicol; NAL, nalidixic acid; NOV, novobiocin.