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. 2018 Sep 25;14(9):e1007316. doi: 10.1371/journal.ppat.1007316

Fig 2. Flow induces more numbers of C. albicans genes having changes in expression level than does temperature.

Fig 2

RNA-seq was performed on Candida albicans wild-type (WT) CAI4 cells grown under microcolony inducing conditions (37°C with flow) and compared to non-microcolony biofilms grown at 37°C without flow (F; 654 gene expression changes) or at 23°C with flow (T; 142 gene expression changes). (A) Gene ontology analysis of both RNA-seq datasets, generated from the Candida Genome Database. Genes may map to multiple ontological categories. (B) Differentially regulated genes from both RNA-seq datasets were hand annotated into five unique categories, with heatmaps of the expression data being shown. Genes with significantly different (Cuffdiff, P<0.05) changes in transcript levels in at least one dataset are shown.