Table 1. Model parameters: Input (upper rows) and output (lower rows).
Notation | Name | Unit | H3N2 | H1N1 |
---|---|---|---|---|
R0 | Basic reproduction number | 1b | 1.8a | 1.46a |
trec | Recovery time | day | 5a | 5a |
Ub | Mutation rate per genome | 1/trec|yr | 5 10−4|0.036c | 8 10−4|0.058c |
a | Crossimmunity distance | AA | 15c | 14c |
K(u) | Crossimmunity function | 1 | |u|/(a + |u|) | |u|/(a + |u|) |
N | Population size | 1 | 108 | 108 |
β | Mutation distrib. parameter | 1 | 2 | 2 |
σ | Average selection coefficient | 1 | 0.048d | 0.028d |
Annual incidence | 1/yr | 0.07d | 0.04d | |
c | Substitution rate | 1/trec|yr | 0.036|2.6a | 0.031|2.26a |
TMRCA2 | Pairwise coalescent time | Year | 3.03a | 4.59a |