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. 2018 Sep 12;14(9):e1007291. doi: 10.1371/journal.ppat.1007291

Table 1. Model parameters: Input (upper rows) and output (lower rows).

Notation Name Unit H3N2 H1N1
R0 Basic reproduction number 1b 1.8a 1.46a
trec Recovery time day 5a 5a
Ub Mutation rate per genome 1/trec|yr 5 10−4|0.036c 8 10−4|0.058c
a Crossimmunity distance AA 15c 14c
K(u) Crossimmunity function 1 |u|/(a + |u|) |u|/(a + |u|)
N Population size 1 108 108
β Mutation distrib. parameter 1 2 2
σ Average selection coefficient 1 0.048d 0.028d
365NitrecN Annual incidence 1/yr 0.07d 0.04d
c Substitution rate 1/trec|yr 0.036|2.6a 0.031|2.26a
TMRCA2 Pairwise coalescent time Year 3.03a 4.59a

a Known from published data for influenza A strains H3N2 and H1N1 [7, 13, 30, 31]

b Unit “1” stands for “dimensionless”.

c Input parameter of the model which was adjusted to fit published data.

d A value predicted for the best-fit parameter set