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. 2018 Sep 26;3(9):12010–12018. doi: 10.1021/acsomega.8b01558

Table 1. Characteristics of Electrochemical BNP Sensing Platformsa.

method interface LOD (pg mL–1) linear range (ng mL–1) ref
LSV immune reaction in solution using AChE-labeled anti-BNP antibodies, detection on silver electrodes by measuring unreacted conjugates from enzymatic reaction 20 000 20–100 (17)
LSV immune reaction in solution with BNP-modified Au NPS detection on a silver electrode modified with thiocholine 20 0.02–0.2 (18)
SPR gold modified with cystamine and BNP and anti-BNP-AChE conjugate 5 0.005–100 (16)
CV SPE modified with Au NPs/BNO antibody and HRP-antibody (sandwich assay) 4 0.014–15 (9)
DPV SPE-aptamer/PEG 0.9 0.0009–1000 this work
EIS silicon nanowells modified with anti-BNP 0.001 0.000001−10 000 (DR) (20)
a

Au NPs, gold nanoparticles; AChE, acetylcholine esterase-labeled antibody; LSV, linear sweep voltammetry; DR, dynamic range.