Figure 2.

Intrahost nucleotide diversity (π) of varicella zoster virus (VZV) across compartments. Nucleotide diversity estimates of the VZV population in each individual sample is shown, grouped by sampled compartment. Median, interquartile range, and maximum-minimum range are marked, as is a dotted red line denoting nucleotide diversities that are 2 SD from the mean (calculated from the nucleotide diversities of all samples). Outlier CSF (red) and plasma (orange) samples are shown. The blue symbol represents the sum diversity of individual vesicles from patient D. Abbreviations: BAL, bronchoalveolar lavage; CSF, cerebrospinal fluid; PLAS, plasma.