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. 2018 Oct 5;8:209. doi: 10.1038/s41398-018-0265-9

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© The Author(s) 2018

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — a Timeline of experiment. b Infusions during LgA self-administration did not differ between groups later treated with CDPPB or Vehicle. c A main effect of treatment was detected, with CDPPB-treated rats exhibiting less presses on the previously active lever. d There was no effect of CDPPB on cue-primed reinstatement, as rats previously treated with CDPPB or vehicle reinstated lever pressing. &p < 0.05 compared to extinction; ^p < 0.05 main effect of treatment. Data are presented as mean ± SEM. n = 6/group