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. 2018 Sep 17;119(6):707–712. doi: 10.1038/s41416-018-0261-0

Table 3.

Reason for treatment discontinuation for metastatic urothelial carcinoma patients receiving everolimus and pazopanib combination at dose levels 1 and 0 (DL-1 and DL0)

Reason for discontinuation Treatment DL-1 (n = 16) N (%) Treatment DL0 (n = 3) N (%) Total (n = 19) N (%)
Adverse event/toxicity 1 (33.3) 1 (5.3)
Progressive disease 14 (87.5) 1 (33.3) 15 (78.9)
Death 1 (6.3) 1 (5.3)
Physician decision 1 (33.3) 1 (5.3)
Patient withdrawal 1 (6.3) 1 (5.3)