Table 3.
Reason for treatment discontinuation for metastatic urothelial carcinoma patients receiving everolimus and pazopanib combination at dose levels 1 and 0 (DL-1 and DL0)
| Reason for discontinuation | Treatment DL-1 (n = 16) N (%) | Treatment DL0 (n = 3) N (%) | Total (n = 19) N (%) |
|---|---|---|---|
| Adverse event/toxicity | — | 1 (33.3) | 1 (5.3) |
| Progressive disease | 14 (87.5) | 1 (33.3) | 15 (78.9) |
| Death | 1 (6.3) | — | 1 (5.3) |
| Physician decision | — | 1 (33.3) | 1 (5.3) |
| Patient withdrawal | 1 (6.3) | — | 1 (5.3) |