Table 3.
ANKRD1 expression levels in lung specimens changed after EGFR-TKI therapy.
| No. | Gender | EGFR mutation | EGFR-TKIs Therapy | Score of Immunostaining (%) | |||
|---|---|---|---|---|---|---|---|
| Baseline | After EGFR-TKI | Fold change | |||||
| 1 | Male | L858R | Gefitinib | 3 months | 78 | 75 | 0.96 |
| 2 | Female | L858R | Afatinib | 5 months | 70 | 84 | 1.2 |
| 3 | Male | Del19 | Gefitinib Erlotinib Afatinib |
5 months 4 months 4 months |
36 | 84 | 2.3 |
| 4 | Female | Del19 | Gefitinib | 22 months | 1 | 98 | 98 |
| 5 | Female | Del19 | Gefitinib | 22 months | 5 | 88 | 17.6 |
| 6 | Female | Del19 | Gefitinib Erlotinib |
10 months 24 months |
1 | 100 | 100 |
| 7 | Male | Del19 | Gefitinib Erlotinib Afatinib |
34 months 4 months 3 months |
0 | 88 | >100 |
| 8 | Female | Del19 | Erlotinib | 50 months | 39 | 78 | 2.0 |
| 9 | Male | Del19 | Gefitinib Afatinib |
48 months 4 months |
13 | 100 | 7.7 |
| 10 | Female | Del19 | Gefitinib Afatinib |
58 months 12 months |
25 | 62 | 2.5 |