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. 2018 Oct 5;8:14896. doi: 10.1038/s41598-018-33190-8

Table 3.

ANKRD1 expression levels in lung specimens changed after EGFR-TKI therapy.

No. Gender EGFR mutation EGFR-TKIs Therapy Score of Immunostaining (%)
Baseline After EGFR-TKI Fold change
1 Male L858R Gefitinib 3 months 78 75 0.96
2 Female L858R Afatinib 5 months 70 84 1.2
3 Male Del19 Gefitinib
Erlotinib
Afatinib
5 months
4 months
4 months
36 84 2.3
4 Female Del19 Gefitinib 22 months 1 98 98
5 Female Del19 Gefitinib 22 months 5 88 17.6
6 Female Del19 Gefitinib
Erlotinib
10 months
24 months
1 100 100
7 Male Del19 Gefitinib
Erlotinib
Afatinib
34 months
4 months
3 months
0 88 >100
8 Female Del19 Erlotinib 50 months 39 78 2.0
9 Male Del19 Gefitinib
Afatinib
48 months
4 months
13 100 7.7
10 Female Del19 Gefitinib
Afatinib
58 months
12 months
25 62 2.5