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. 2018 Aug 17;119(6):737–743. doi: 10.1038/s41416-018-0231-6

Table 4.

Hazard ratios for survival from stepwise, backward, and multivariate Cox hazard regression after multiple imputation (40 imputations)

HR 95% Confidence interval p value
Age 1.013 1.007–0.019 <0.001
Location skeleton 0.167 1.010–1.349 0.036
Category 1 (slow growth) Reference
Category 2 (moderate growth) 1.580 1.318–1.895 <0.001
Category 3 (rapid growth) 2.918 2.450–3.475 <0.001
Other bone metastases 1.201 1.029–1.401 0.020
Visceral metastases 1.544 1.333–1.789 <0.001
Previous systemic therapy 1.233 1.063–1.431 0.006
Hemoglobin 0.890 0.851–0.931 <0.001
NLR 1.311 1.117–1.538 0.001
PLR 1.358 1.152–1.601 <0.001

NLR neutrophil-to-lymphocyte ratio, PLR  platelet-to-lymphocyte ratio