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. 2018 Oct 5;9:4112. doi: 10.1038/s41467-018-06567-6

Fig. 4.

Fig. 4

Multivariate Cox regression assessing the effect BVZ while stratifying for CNA cluster membership. ad Kaplan-Meier plots and multivariate Cox regression with hazard ratios, 95% confidence intervals and P-values are shown while correcting for the relevant covariates in mCRC receiving chemotherapy + BVZ while stratifying for CNA cluster 1 (a), cluster 2 (b), cluster 3 (c) and cluster 2 + 3 versus cluster 1 (d). Effects were only significant for the latter 3 comparisons. Doublet stands for mono-chemotherapy (FP) or a combination of chemotherapy (FP-OX, FP-IRI)