Table 1.
Characteristic | Control | CAD | IS | P 1 | P 2 | P 3 |
---|---|---|---|---|---|---|
Number | 549 | 568 | 537 | |||
Male/female | 384/165 | 419/149 | 389/148 | 0.155 | 0.364 | 0.619 |
Age, years | 61.87±11.12 | 62.23±10.59 | 62.80±12.41 | 0.589 | 0.196 | 0.408 |
Body mass index, kg/m2 | 22.28±2.82 | 23.85±3.37 | 23.43±3.52 | <0.001 | <0.001 | 0.041 |
Systolic blood pressure, mmHg | 130.00±20.60 | 132.97±23.16 | 147.58±21.96 | 0.024 | <0.001 | <0.001 |
Diastolic blood pressure, mmHg | 82.38±13.01 | 79.05±14.06 | 83.71±12.95 | <0.001 | 0.092 | <0.001 |
Pulse pressure, mmHg | 49.53±14.92 | 53.83±17.59 | 63.83±17.96 | <0.001 | <0.001 | <0.001 |
Cigarette smoking, n (%) | 235 (42.8) | 246 (43.3) | 224 (41.7) | 0.865 | 0.716 | 0.592 |
Alcohol consumption, n (%) | 245 (44.6) | 132 (23.2) | 144 (26.8) | <0.001 | <0.001 | 0.170 |
Total cholesterol, mmol/L | 4.92±1.11 | 4.51±1.23 | 4.52±1.14 | <0.001 | <0.001 | 0.836 |
Triglyceride, mmol/L | 1.01 (0.64) | 1.36 (0.94) | 1.35 (0.93) | <0.001 | <0.001 | 0.467 |
HDL-C, mmol/L | 1.90±0.49 | 1.14±0.34 | 1.23±0.40 | <0.001 | <0.001 | <0.001 |
LDL-C, mmol/L | 2.74±0.79 | 2.71±1.01 | 2.68±0.90 | 0.549 | 0.245 | 0.638 |
Apolipoprotein (Apo) A1, g/L | 1.40±0.24 | 1.04±0.52 | 1.02±0.22 | <0.001 | <0.001 | 0.608 |
ApoB, g/L | 0.90±0.21 | 1.11±0.75 | 0.89±0.25 | 0.313 | 0.502 | 0.302 |
ApoA1/ApoB | 1.63±0.47 | 1.34±0.46 | 1.17±0.61 | 0.009 | <0.001 | 0.117 |
Type 2 diabetes, n (%) | 43 (7.8) | 91 (16.0) | 81 (15.1) | <0.001 | <0.001 | 0.668 |
Hypertension, n (%) | 157 (28.6) | 200 (35.2) | 285 (53.1) | 0.018 | <0.001 | <0.001 |
Hyperlipidemia, n (%) | 175 (31.9) | 220 (38.7) | 238 (44.3) | 0.017 | <0.001 | 0.100 |
CAD coronary artery disease, IS ischemic stroke, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol. The value of triglyceride was presented as median (interquartile range), the difference between CAD/IS patients and controls was determined by the Wilcoxon-Mann-Whitney test. P1, CAD vs. controls; P2, IS vs. controls; P3, CAD vs. IS