Table 1.
Population characteristics at day 1 (n = 278)
| Population characteristics at day 1 (n = 278) |
Cohort n = 278 |
Non-survivors n = 84 |
Survivors n = 194 |
P value |
|---|---|---|---|---|
| Patient age (years) | 64.4 ± 15.5 | 70.1 ± 14.5 | 61.9 ± 15.3 | <0.0001 |
| Male, n (%) | 169 (60.8) | 62 (73.8) | 107 (55.2) | 0.003 |
| Body mass index (kg/m2)a | 25.3 ± 5.8 | 25.2 ± 5.2 | 25.4 ± 6.1 | 0.791 |
| McCabe score at day 1, n (%) | 252 (90.7) | 72 (85.7) | 180 (92.8) | 0.063 |
| History of: | ||||
| Cardiac disease, n (%) | 138 (49.6) | 53 (63.1) | 85 (43.8) | 0.003 |
| Respiratory disease, n (%) | 154 (55.4) | 44 (52.4) | 110 (56.7) | 0.506 |
| Diabetes mellitus, n (%) | 58 (20.9) | 22 (23.8) | 36 (18.6) | 0.150 |
| Renal disease, n (%) | 17 (6.1) | 9 (10.7) | 8 (4.1) | 0.035 |
| Immunologic disease, n (%) | 34 (12.2) | 9 (10.7) | 25 (12.9) | 0.612 |
| Fine’s score | 143.9 ± 41.5 | 163.9 ± 35.3 | 135.3 ± 41.1 | <0.0001 |
| SOFA score day 1 | 9.8 ± 3.7 | 11.6 ± 4.1 | 9.1 ± 3.2 | <0.0001 |
| SAPS II | 52.9 ± 17.7 | 62.6 ± 17.2 | 48.7 ± 16.3 | <0.0001 |
| Norepinephrine at admission, n (%) | 207 (74.5) | 65 (77.4) | 142 (73.2) | 0.462 |
| Mechanical ventilation day 1, n (%) | 199 (71.6) | 71 (84 .5) | 128 (65.9) | 0.002 |
| Renal replacement therapy day 1, n (%) | 30 (10.8) | 21 (25.0) | 9 (4.6) | <0.0001 |
| Septicaemia, n (%) | 117 (42.1) | 38 (45.2) | 79 (40.7) | 0.484 |
| Hydrocortisone, n (%) | 167 (60.1) | 59 (70.2) | 108 (55.7) | 0.023 |
| Drotrecogin, n (%) | 41 (14.8) | 17 (20.2) | 24 (12.4) | 0.089 |
| Length of stay (days) | ||||
| ICU | 18.5 ± 19.14 | 16.7 ± 23.0 | 19.3 ± 17.2 | 0.298 |
| Hospital | 28.9 ± 26.3 | 18.7 ± 25.8 | 33.5 ± 25.3 | <0.0001 |
Description of the population according to the status of patients at hospital discharge: survivors (n = 194) or non-survivors (n = 84). The mean ± standard deviation was reported for continuous variables. The number of patients in each category and the corresponding percentages are given for categorical variables. P values were obtained using chi square statistics for qualitative variables and the unpaired and two-sided Student’s t test for continuous ones
SOFA Sepsis-related Organ Failure Assessment, SAPS Simplified Acute Physiology Score
a19 values were missing for body mass index