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. 2018 Oct 5;19:198. doi: 10.1186/s12931-018-0901-1

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 7 — Comparison of the effect of VX-770/VX-809/FSK and TMX/ATP on CFBE cell current density. A: example of current/voltage relationships of cells in control conditions (squares), in the presence of VXs/FSK triangles) and in those treated with TMX/ATP (circles). B: The combination of TMX + ATP (n = 8) showed greater efficiency than VXs/FSK at increasing chloride membrane currents (n = 7; p < 0.001). Both treatments elicited highly significant increases in current density compared to the density in control conditions (n = 12)