Table 2.
IGFBP3 rs2854744 genotype distribution in acromegaly patients and controls
| Genotype | Case [N(%)]a | Control [N(%)]b | MAF | PHWE | OR (95% CI) | P |
|---|---|---|---|---|---|---|
| AA | 63(63) | 72(50.7) | 0.262 | 0.236 | 1 | |
| AC | 33(33) | 54(38) | 0.698(0.403–1.21) | 0.2 | ||
| CC | 4(4) | 16(11.3) | 0.286(0.091–0.899) | 0.032 | ||
| A allele | 159(79.5) | 198(69.7) | 1 | |||
| C allele | 41(20.5) | 86(30.3) | 0.594(0.388–0.909) | 0.016 |
aGenotypic data for 100 subjects in the case group were available. bGenotypic data for 142 subjects in the control group were available. MAF minor allele frequency, HWE Hardy-Weinberg equilibrium. Significant associations are marked in bold