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. 2018 Oct 5;37:245. doi: 10.1186/s13046-018-0915-z

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Proteome characterization by HPLC-MS/MS of control and pH 6.0 exosome obtained after ultracentrifugation. a Venn diagram depicting the overlap of upregulated and downregulated pH 6.0 proteins with respect to control condition. b Functional analysis of the downregulated, equally expressed and upregulated proteins at pH 6.0. Only over-represented metabolic pathways with P ≤ 10^− 2 were considered. c GO enrichments of pH 6.0 upregulated proteins. Only over-represented categories with P ≤ 10^− 2 were considered