Table 3.
Comparison of demographic and clinical data between those with and without systemic exertion intolerance disease (SEID)
| Characteristic | All Patients (n=187) | SEID (n=39) | No SEID (n=148) | DF | t-value or chi-square | P value |
|---|---|---|---|---|---|---|
| Age, years | 36.1 (15.1) | 35.9 (14.1) | 36.1 (15.4) | 185 | 0.1 | 0.94 |
| Body mass index | 26.4 (6.2) | 26.2 (5.6) | 26.5 (6.3) | 167 | 0.3 | 0.77 |
| Women, % | 63.1 | 66.7 | 62.2 | 1 | 0.3 | 0.60 |
| Age of EDS Onset, years | 21.4 (13.0) | 21.6 (10.6) | 21.4 (13.6) | 169 | -0.1 | 0.89 |
| Sleep time/week, hours | 64.4 (19.7) | 68.3 (20.4) | 63.3 (19.4) | 185 | −1.4 | 0.16 |
| TST, minutes | 434.9 (100.5) | 438.0 (77.1) | 434.1 (106.0) | 71 | −0.2 | 0.81 |
| Sleep efficiency | 87.5 (8.9) | 86.4 (9.5) | 87.8 (8.7) | 162 | 0.8 | 0.42 |
| PSG N1% | 6.1 (4.0) | 6.5 (4.7) | 5.9 (3.8) | 134 | −0.7 | 0.47 |
| PSG N2% | 59.7 (12.4) | 63.4 (12.3) | 58.7 (12.2) | 128 | −1.8 | 0.07 |
| PSG N3% | 15.5 (10.3) | 13.1 (11.1) | 16.1 (10.1) | 128 | 1.4 | 0.17 |
| PSG REM% | 19.0 (9.0) | 17.3 (8.9) | 19.4 (9.0) | 138 | 1.1 | 0.27 |
| AHI | 2.9 (5.0) | 4.3 (6.9) | 2.4 (4.2) | 40 | −1.5 | 0.13 |
| PLMI | 8.5 (16.0) | 8.1 (15.6) | 8.6 (16.2) | 134 | 0.1 | 0.90 |
| MSLT-SOL | 6.7 (4.3) | 6.6 (4.5) | 6.7 (4.3) | 156 | 0.2 | 0.87 |
| Number of SOREMPs | 1.1 (1.4) | 1.1 (1.3) | 1.0 (1.5) | 155 | −0.2 | 0.87 |
| GABA Percent Potentiation | 98.6 (21.6) | 100.7 (23.6) | 97.7 (21.0) | 43 | −0.4 | 0.68 |
Values are reported as mean (SD) or percentage. DF: degrees of freedom; Sleeptime/week: patient reported summed hours of sleep during a typical week, including weekdays and weekends; TST: total sleep time on PSG; PSG: polysomnogram; AHI: apnea-hypopnea index; PLMI: periodic limb movement index; MSLT-SOL: MSLT mean sleep latency; SOREMP: sleep onset REM periods on polysomnography/multiple sleep latency test. GABA Percent Potentiation: percent potentiation by cerebrospinal fluid on GABA-A receptors in vitro (Rye et al, 2012).