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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Med Res Rev. 2018 May 4;38(6):1974–2023. doi: 10.1002/med.21503

Figure 19.

Figure 19

Chemical structures of benzamidine-based inhibitors of FXIa 84–92. A) Inhibitors 84–89 are also potent inhibitors of FVIIa. B) Inhibitors 90–92 are also potent inhibitors of APC. Provided are inhibitors’ Ki and IC50 values in nM and μM.