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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Med Res Rev. 2018 May 4;38(6):1974–2023. doi: 10.1002/med.21503

Figure 25.

Figure 25

Chemical structures of A) unmodified DNA or RNA sequence having ribose or deoxyribose sugar and phosphodiester linkage and B) modified oligonucleotide sequence used in the design of FXI ASO with 2′-methoxyethylribose sugar and phosphorothioate linkage. NB means nitrogenous base.