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Effects of genistein exposure on gene expression of Esr1 and Esr2 in mice treated with 0, 300, 500, or 1000 ppm genistein. Gene expression was measured after 30, 60, 150, and 240 days of exposure to genistein. RNA was extracted from snap-frozen ovaries, reversed transcribed to cDNA, and subjected to quantitative real time PCR. Graphs represent means ± SEM from 3 females per treatment group.
