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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Gastroenterology. 2018 Jun 15;155(4):1177–1191.e16. doi: 10.1053/j.gastro.2018.06.034

Figure 1.

Figure 1

IL23 Expression by CX3CR1+ Cells Induces Colonic and Cecal Inflammation. (A) Tamoxifen (TAM) in diet 2019 (green) was fed to R23FR and FR mice during the indicated times. After each cycle of TAM treatment, animals were switched to our mouse facility diet 5053 (gray). (B) Representative H&E-stained cecum and colon sections of R23FR mice at different time points. Scale bars, 100 μm. (C) Fecal lipocalin-2 levels in the stools of R23FR and FR mice were measured by ELISA (n= 5–15 per group per time point). (D) Histological scores of the colon and cecum of R23FR and FR mice at different time points (n= 5–15 per group per time point). Error bars represent mean ± SEM.