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. 2018 Oct 1;9:2214. doi: 10.3389/fimmu.2018.02214

Figure 1.

Figure 1

Summary of HCMV-encoded NK modulators discussed in this review. Host proteins are labeled in black; HCMV proteins in red (found in UL/b′ region), green (variable outside UL/b′) or yellow (conserved outside UL/b′); sp = signal peptide. Arrows and lines represent actions. Solid black arrow = intracellular NK activation signal; dotted black arrow = intracellular NK inhibition signal; gray arrow = extracellular signal to target; red line = impairs surface expression; red arrow = disrupts intracellular expression; blue arrow = increases surface expression.