Table 5.
Effect of MEMARB on the redox status - Activity levels of antioxidant enzymes.
| Group | GPx (nM GSH consumed/min/mg protein) |
SOD (U/mg protein) |
Catalase (U/mg protein) |
|---|---|---|---|
| Pancreas | Pancreas | Pancreas | |
| Normal Control | 324.5 ± 42.5 | 14.2 ± 1.49 | 114.4 ± 15.90 |
| MEMARB Control | 339.2 ± 40.02NS | 14.5 ± 1.65NS | 112.1 ± 16.37NS |
| EtOH + Cerulein | 233.6 ± 29.43* | 8.2 ± 0.97* | 72.8 ± 7.79* |
| EtOH + Cerulein + MEMARB | 353.33 ± 46.29* | 11.7 ± 1.51* | 106.3 ± 12.65* |
Data were analysed by one-way ANOVA followed by post-hoc Bonferroni test. Values are expressed as mean ± S.D. of 6 rats in each group. Statistical significance was calculated by comparing normal control vs. MEMARB control; Control vs. EtOH + Cerulein; EtOH + Cerulein vs. EtOH + Cerulein + MEMARB. *p = 0.000; NS non-significant.