Table 3.
Correlation between clinical characteristics and gut microbiota.
| Genusb | ALTa | ASTa | LDHa | CKa | Lymphadenopathy | Diarrhea | Vomiting | Infection | Mortality |
|---|---|---|---|---|---|---|---|---|---|
| Prevotella | 0.39∗ | 0.37 | -0.04 | -0.30 | -0.10 | 0.12 | 0.28 | 0.23 | 0.31 |
| SMB53 | 0.16 | 0.34 | 0.18 | -0.06 | -0.24 | 0.05 | 0.06 | 0.17 | 0.18 |
| Veillonella | 0.19 | 0.21 | 0.20 | -0.07 | 0.05 | 0.24 | 0.12 | 0.46∗ | 0.21 |
| Ruminococcus | -0.09 | -0.11 | -0.31 | -0.40∗ | 0.01 | 0.05 | -0.12 | 0.10 | -0.03 |
| Faecalibacterium | 0.16 | 0.23 | 0.20 | -0.11 | 0.31 | 0.03 | 0.16 | 0.32 | 0.37 |
| Anaerostipes | -0.01 | 0.19 | 0.17 | 0.21 | 0.25 | -0.06 | -0.09 | -0.10 | -0.23 |
| Blautia | 0.13 | 0.21 | 0.12 | -0.07 | 0.05 | 0.11 | 0.08 | 0.08 | 0.04 |
| Coprococcu | 0.22 | 0.12 | -0.06 | -0.12 | -0.30 | 0.03 | -0.01 | -0.02 | 0.02 |
| Lachnospira | 0.66∗∗ | 0.56∗∗ | 0.16 | -0.09 | -0.46∗ | 0.11 | 0.05 | 0.34 | 0.25 |
| Roseburia | 0.16 | 0.25 | 0.08 | -0.07 | -0.03 | 0.15 | 0.02 | 0.08 | 0.07 |
| Enterococcu | -0.19 | -0.19 | -0.17 | 0.01 | 0.12 | -0.12 | -0.14 | -0.04 | 0.10 |
| Lactobacillus | 0.42∗ | 0.35 | -0.20 | -0.08 | -0.57∗∗ | 0.23 | 0.31 | 0.09 | 0.20 |
| Streptococcus | 0.14 | 0.24 | 0.12 | -0.20 | -0.05 | 0.12 | 0.41∗ | 0.21 | 0.48∗ |
| Escherichia | 0.25 | 0.30 | 0.27 | 0.20 | 0.02 | -0.15 | 0.08 | 0.25 | 0.03 |
| Sutterella | 0.90 | -0.12 | -0.13 | -0.26 | -0.01 | 0.10 | -0.16 | 0.14 | 0.07 |
aALT, alanine transaminase, AST, aspartate transaminase, CK, creatine kinase, LDH, lactate dehydrogenase. bThe correlation between clinical characteristics and gut microbiota had been analyzed at the bacterial genus level. ∗∗∗Correlation between clinical characteristics and gut microbiota at the genus level in SFTS patients, r represents Spearman correlation coefficient, with r value of 0–0.3, 0.3–0.5, and >0.5 indicating weak, moderate and strong correlation between the two variables, respectively. ∗ and ∗∗ represents P < 0.05 and P < 0.01, respectively.