Table 4.
Univariate and multivariate Cox proportional hazard model for appropriate ICD/CRT‐D therapy
| Univariate | Multivariate | |||||||
|---|---|---|---|---|---|---|---|---|
| HR | 95% CI | P value | HR | 95% CI | P value | |||
| Age | 1.00 (per 1 y.o.) | 0.99 | 1.02 | .746 | ||||
| Male (vs Female) | 1.14 | 0.83 | 2.35 | .227 | ||||
| IHD (vs non‐IHD) | 1.19 | 0.73 | 1.89 | .484 | ||||
| Sustained VT (vs CPA) | 2.86 | 1.77 | 4.76 | <.001 | 2.80 | 1.60 | 4.46 | .001 |
| Cardiac death | 1.12 | 0.60 | 2.07 | .724 | ||||
| BNP | 1.00 (per 1 pg/mL) | 0.24 | 3.25 | .988 | ||||
| LVEF | 0.98 (per 1.0%) | 0.97 | 1.00 | .016 | 0.98 (per 1.0%) | 0.97 | 1.01 | .066 |
| Amiodarone | 0.68 | 0.43 | 1.06 | .087 | ||||
| Sotalol | 3.01 | 1.49 | 5.52 | .003 | ||||
| Bepridil | 2.95 | 0.72 | 8.03 | .117 | ||||
| Class I AAD | 1.91 | 1.19 | 3.00 | .007 | 1.56 | 0.96 | 2.48 | .070 |
| β‐blocker | 0.92 | 0.58 | 1.48 | .721 | ||||
| Verapamil | 2.04 | 0.94 | 3.88 | .068 | ||||
| Diltiazem | 0.90 | 0.15 | 2.87 | .885 | ||||
| Digitalis | 1.22 | 0.37 | 2.94 | .709 | ||||
| ACE‐I/ARB | 1.53 | 0.98 | 2.40 | .060 | ||||
AAD, antiarrhythmic drug; ACE‐I, angiotensin‐converting enzyme inhibitor; ARB, angiotensin receptor blocker; BNP, brain natriuretic peptide; CPA, cardiopulmonary arrest; CRT‐D, cardiac resynchronization therapy with defibrillator; HR, hazard ratio; ICD, implantable cardioverter‐defibrillator; IHD, ischemic heart disease; LVEF, left ventricular ejection fraction; VT, ventricular tachycardia.