Table 3.

Ordinal Regression Analysis: Interviewer‐rated Best‐fit Model

Parameter	Hypothesis Test			OR	95% Wald CI for OR
	Wald ${\mathit{\chi }}^2$	df	P Value		Lower	Upper
Age	10.882	1	0.001	1.015	1.006	1.023
Premanifest vs. stage IV or V	11.125	1	0.001	0.313	0.159	0.620
Stage I vs. stage IV or V	11.261	1	0.001	0.390	0.225	0.676
Stage II vs. stage IV or V	8.567	1	0.003	0.493	0.307	0.792
Stage III vs. stage IV or V	10.650	1	0.001	0.510	0.341	0.764
Female vs. male	8.130	1	0.004	1.366	1.103	1.693
Dementia vs. no dementia	4.437	1	0.035	0.716	0.525	0.977
Motor score	2.614	1	0.106	0.993	0.985	1.001
IR anxiety	12.707	1	0.000	1.064	1.029	1.102
IR depression	7.270	1	0.007	1.047	1.013	1.083
IR irritability	8.804	1	0.003	1.051	1.017	1.087

CI, confidence interval, IR, interviewer‐rated; OR, odds ratio; df, degrees of freedom.