Fig. 1.

Pedigree of family AMI1 segregating autosomal dominant hypomineralized amelogenesis imperfecta. Affected males and females are indicated by filled squares and circles, respectively. The proband is marked by the arrow. The genotypes of the microsatellite markers that were used to define the candidate interval are shown below each individual used in the linkage analysis screen. The black bar represents the marker haplotype that tracks with the affected status, and the grey bar indicates the marker haplotype that tracks with the unaffected status. White bars indicate marker haplotypes acquired from individuals who married into family AMI1