Table 2.

A comprehensive summary of indications for AATD testing across documents for the clinical management of chronic respiratory disease

Document	Disease	Indications for AATD testing
Global strategy for prevention, diagnosis and management of COPD, 2018 [49]	COPD	All patients with a diagnosis of COPD, especially in areas with high AATD prevalence
Global strategy for asthma management and prevention, 2018 [50]	Asthma	No indication for AATD testing
European Respiratory Society, 2017 [54]	Bronchiectasis	Patients with basal emphysema or early onset airflow obstruction
Pulmonology Portuguese Society Bronchiectasis Study Group, 2018 [53]	Bronchiectasis	All patients with a diagnosis of BE
Thoracic Society of Australia and New Zealand, 2015 [62]	Bronchiectasis	No indication for AATD testing
British Thoracic Society, 2010 [51]	Bronchiectasis	Patients with basal emphysema.
Normativa SEPAR, 2008 [52]	Bronchiectasis	Patients with emphysema and /or liver disease